tert-Butyl (R)-3-(methylsulfonyloxy)pyrrolidine-1-carboxylate
1-Pyrrolidinecarboxylic acid, 3-[(methylsulfonyl)oxy]-, 1,1-dimethylethylester, (3R)-
CAS: 127423-61-4
Molecular Formula: C10H19NO5S
tert-Butyl (R)-3-(methylsulfonyloxy)pyrrolidine-1-carboxylate - Names and Identifiers
tert-Butyl (R)-3-(methylsulfonyloxy)pyrrolidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C10H19NO5S |
| Molar Mass | 265.33 |
| Storage Condition | 2-8°C |
| MDL | MFCD06809586 |
tert-Butyl (R)-3-(methylsulfonyloxy)pyrrolidine-1-carboxylate - Introduction
(R)-1-Boc-3-methanesulfonyloxypyrrolidine is an organic compound with the following properties:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C12H18N2O4S
-Molecular weight: 298.35g/mol
-melting point: 95-98 ℃
Use:
- (R)-1-Boc-3-methanesulfonyloxypyrrolidine is commonly used as a chiral intermediate and is widely used in organic synthesis.
-It can be used as a catalyst for the synthesis of drugs, natural products and chemical reactions.
Preparation Method:
The preparation of (R)-1-Boc-3-methanesulfonyloxypyrrolidine is usually carried out by the following steps:
1. Reaction of (D)-pyrrolidine with methylamine to give (1R)-methanesulfonyloxypyrrolidine.
2. Reaction of (1R)-methanesulfonyloxypyrrolidine with di-tert-butyl carbonate to obtain (R)-1-Boc-3-methanesulfonyloxypyrrolidine.
Safety Information:
- (R)-1-Boc-3-methanesulfonyloxypyrrolidine may be irritating to skin, eyes, and respiratory tract. Avoid direct exposure when in contact.
-Wear appropriate protective gloves, glasses and a mask when handling the compound.
-In use or storage, should avoid high temperature, fire and oxidant contact.
Please note that the above information is for reference only. When using and handling chemicals, the corresponding prohibition and safe operation procedures should be strictly observed.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C12H18N2O4S
-Molecular weight: 298.35g/mol
-melting point: 95-98 ℃
Use:
- (R)-1-Boc-3-methanesulfonyloxypyrrolidine is commonly used as a chiral intermediate and is widely used in organic synthesis.
-It can be used as a catalyst for the synthesis of drugs, natural products and chemical reactions.
Preparation Method:
The preparation of (R)-1-Boc-3-methanesulfonyloxypyrrolidine is usually carried out by the following steps:
1. Reaction of (D)-pyrrolidine with methylamine to give (1R)-methanesulfonyloxypyrrolidine.
2. Reaction of (1R)-methanesulfonyloxypyrrolidine with di-tert-butyl carbonate to obtain (R)-1-Boc-3-methanesulfonyloxypyrrolidine.
Safety Information:
- (R)-1-Boc-3-methanesulfonyloxypyrrolidine may be irritating to skin, eyes, and respiratory tract. Avoid direct exposure when in contact.
-Wear appropriate protective gloves, glasses and a mask when handling the compound.
-In use or storage, should avoid high temperature, fire and oxidant contact.
Please note that the above information is for reference only. When using and handling chemicals, the corresponding prohibition and safe operation procedures should be strictly observed.
Last Update：2024-04-09 15:17:51
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CAS: 127423-61-4
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CAS: 127423-61-4
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